Multiple autoimmune phenomna preceding a lymphoproliferative disorder
نویسندگان
چکیده
منابع مشابه
Multiple autoimmune phenomena preceding a lymphoproliferative disorder.
Karunatilake and Pidcock [1] recently described an interesting patient with autoimmune manifestations, cytopenias and lymphoproliferation. However, the authors did not comment on several important aspects. Did the patient have any lymphadenopathy, and was there a family history of a similar condition? Was the presence of double negative T cells in the peripheral blood looked for, was an aptotos...
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Autoimmune lymphoproliferative Syndrome (ALPS) is a rare inherited disorder of apoptosis. It usually presents with chronic lymphadenopathy, splenomegaly, and symptomatic cytopenia in a child. Herein, we report a 14-year-old boy with symptoms misdiagnosed as hemophagocytic lymphohistiocytosis who was treated before ALPS was diagnosed for the patient. This case should alert pediatricians to consi...
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PURPOSE OF REVIEW The autoimmune lymphoproliferative syndrome is a recently identified human disorder of lymphocyte apoptosis that has provided important information about Fas-mediated lymphocyte apoptosis. In this review we summarize current information regarding the diagnosis, management and underlying molecular basis of the syndrome. RECENT FINDINGS The genetic basis of autoimmune lymphopr...
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1»Titu Maiorescu« University, Faculty of Medicine, Department of Physiology, Center for Rheumatic Diseases, Bucharest, Romania 2»Carol Davila« University of Medicine and Pharmacy, Clinic of Neurology, Colentina Clinical Hospital, Bucharest, Romania 3University of Medicine and Pharmacy, Department of Immunology, Craiova, Romania 4»Carol Davila« University of Medicine and Pharmacy, Clinical Hospi...
متن کاملautoimmune lymphoproliferative syndrome; a case report
autoimmune lymphoproliferative syndrome is a disorder of lymphoid system regulation characterized by chronic splenomegaly, lymphadenopathy and autoimmune phenomena especially immune-mediated cytopenias. the hallmark of the disease is the presence in peripheral blood and lymphoid tissue of increased numbers of a normally rare t lymphocyte subset, usually referred to as “double-negative” t cells....
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ژورنال
عنوان ژورنال: Ceylon Medical Journal
سال: 2009
ISSN: 2386-1274,0009-0875
DOI: 10.4038/cmj.v52i3.974